The new, enhanced LSA Assays deliver increased coverage, optimized performance, and improve the overall workflow of the LIFECODES^® HLA Antibody Analysis portfolio.

Performance

• Expanded antigen panels enable laboratories to more comprehensively determine the sample’s antibody profile.
• An option to use a higher serum-bead dilution ratio significantly increases MFI values, especially in the 1,000-5,000 MFI range.
• A new, LSA Class II bead blocker reduces non-specific reactivity thus resulting in fewer false positive reactions.

Accuracy

• All antigen values are now normalized to an external standard, which enables greater lot to lot reproducibility.
• A new calculation for positive/negative assignments has been shown to reduce both inter and intra site variability.

Workflow

• The LSA Wash Buffer has been aligned with the Wash Buffer used in in the LIFECODES^® Screen and Class I/II ID assays. This simplifies the workflow for laboratories that use multiple products from the LIFECODES® Antibody Analysis portfolio.

The LIFECODES LSA Single Antigen and C3d Detection kits are CE marked for In Vitro Diagnostic Use.