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Capture-R® Ready-Screen®

Immucor’s Capture-R Ready-Screen product line offers automated detection of unexpected red blood cell antibodies. Capture’s IgG specific technology provides high sensitivity for clinically significant antibodies, without the noise of IgM antibodies. To improve efficiency, reagent red blood cells are bound to test wells at the time of manufacture so there are no liquid reagent red blood cells to manage.​

Benefits of Capture Technology: ​​​​

Ease of Use

  • Ready to use reagents
  • Antigens are pre-coated on microwells
  • No special pipettes or precision pipetting
  • Consistent procedures across assays
  • Long shelf life for better inventory management

Performance & Productivity

  • IgG specific technology
  • High sensitivity for clinically significant RBC antibodies – compares to enzyme methods without the added work
  • Multiple assays for red blood cells, platelet and CMV
  • Comprehensive and broad automated test menu with quick turnaround times and high throughput

Flexible

  • A wash step allows for the use of slightly lipemic or hemolyzed samples
  • Reports describe the use of Immucor products to help mitigate interference with monoclonal antibody therapies1,2
  • Run single sample or a full batch

​Multiple options in automated identification of red blood cell antibodies: ​​

Product Description
Capture-R Ready-Screen
(I and II)
Contains alternating wells coated with red cell membranes from one of two group O donors. Each strip consists of eight individual wells to perform four (2-cell) antibody screens. Dia and Cw positive cells available.
Capture-R Ready-Screen (3) Contains alternating wells coated with red cell membranes from one of two group O donors. Each strip consists of eight individual wells to perform two (3-cell) antibody screens. The fourth well of each antibody screen consists of a built-in positive control, a dried cell that is sensitized with IgG anti-D. Dia, Cw and Mia positive cells available.
Capture-R Ready-Screen (Pooled) Each well is coated with red cell membranes prepared from a pool of two Group O donors. Each strip consists of eight individual wells to perform eight antibody screens. Dia and Cw positive cells available.

Consistent and Accurate Manufacturing:

  • Immucor has a rich supply of donors. Our database of over 10,000 typed donors is utilized to create the best antigen profile on every lot.
  • Our donors are phenotyped by two separate laboratories using unique reagents.
  • We apply our experience with molecular immunohematology (MIH) to enhance the value of our serological products. Each donor’s full antigen profile, including extended antigen typing by DNA analysis is provided on the Supplemental Unit Typings (SUT) with each antibody identification panel.
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*Product offerings may differ by region, please check with your local Immucor representative for regulatory status in your area. ​​​​​​​​​​​​​​​

1. Howard-Menk C, Crane JE, Doshi L, Papari M. HU5F9-G4 Monoclonal Anti-CD47 Therapy: A First Experience with Interference in Antibody Identification. Transfusion 2018; 58 [S2]:177A. ​​​​​​​​​​​​​​​

2. De Vooght KMK, Lozano M, Bueno JL, et al. Vox Sanguinis International Forum on typing and matching strategies in patients on anti-CD38 monoclonal therapy: summary. Vox Sanguinis 2018; 113:492-498.

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